Cella Virus Packaging

CRISPR-Cella Virus Packaging

Lentivirus packaging

Recombinant lentivirus is the most commonly used viral vector for efficient gene delivery into mammalian cells. Unlike plasmid DNA vector which only allows transient and episomal expression of the foreign gene in the host cell, lentiviral vector can achieve permanent expression of the foreign gene through integration into the host cell genome. Lentivirus is also efficient for in vivo gene delivery.Cellalabs provides end-to-end lentiviral vector design and packaging services with superior quality driven by a blend of proprietary technologies and reagents.

Adeno-associated virus packaging

Adeno-associated virus (AAV) has been an increasingly important viral vector for gene therapy and cell therapy. AAV belongs to the Dependovirus genus, meaning that it depends on a co-infecting helper virus (usually adenovirus) for productive infection to occur. Additionally, the recombinant AAV genome has two essential genes removed to prevent integration and replication to make AAV a safe and effective tool for gene delivery. Cellalabs provides end-to-end AAV vector design and packaging services with superior quality driven by a blend of proprietary technologies and reagents.

Quality control

Quality control includes titer measurement, sterility testing for bacteria and fungi, and mycoplasma detection besides safety testing through measuring endotoxin level by gel clot assay. Additional QC should be added depending on the projects.

Service Details